An induced pluripotent stem cell line (CSUi004-A) from skin fibroblasts of a healthy individual
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چکیده
منابع مشابه
Establishment of a pancreatic stem cell line from fibroblast-derived induced pluripotent stem cells
BACKGROUND For cell therapies to treat diabetes, it is important to produce a sufficient number of pancreatic endocrine cells that function similarly to primary islets. Induced pluripotent stem (iPS) cells represent a potentially unlimited source of functional pancreatic endocrine cells. However, the use of iPS cells for laboratory studies and cell-based therapies is hampered by their high tumo...
متن کاملDerivation of a disease-specific human induced pluripotent stem cell line from a biliary atresia patient
Biliary atresia (BA) is a common cause of pediatric end-stage liver disease. While its etiology is not yet clear, evidence has suggested that BA results from interactions between genetic susceptibility and environmental factors. Disease relevant human cellular models of BA will facilitate identification of both genetic and environmental factors that are important for disease prevention and trea...
متن کاملCorrection: Negligible Immunogenicity of Induced Pluripotent Stem Cells Derived from Human Skin Fibroblasts
The following information is missing from the Funding statement: Area of Excellence program (AoE/M-12/06), University Grants Committee of Hong Kong Special Administrative Region. The complete, correct Funding statement is as follows: This work was supported in part by the grants from National Natural Science Foundation of China (NSFC) and the Research Grants Council (RGC) of Hong Kong Joint Res...
متن کاملDerivation of Induced Pluripotent Stem Cells from Fetal Human Skin Fibroblasts
The isolation and study of autologous human stem cells remain among the most urgent problems in cell biology and biomedicine to date. Induced pluripotent stem cells can be derived from human somatic cells by the overexpression of a number of genes. In this study we reprogrammed fetal human skin fibroblasts by transduction with retroviral vectors carrying murine Oct4 , Sox2 , Klf4 , and c...
متن کاملNegligible Immunogenicity of Induced Pluripotent Stem Cells Derived from Human Skin Fibroblasts
Human induced pluripotent stem cells (hiPSCs) have potential applications in cell replacement therapy and regenerative medicine. However, limited information is available regarding the immunologic features of iPSCs. In this study, expression of MHC and T cell co-stimulatory molecules in hiPSCs, and the effects on activation, proliferation and cytokine production in allogeneic human peripheral b...
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ژورنال
عنوان ژورنال: Stem Cell Research
سال: 2021
ISSN: 1873-5061
DOI: 10.1016/j.scr.2021.102336